We are going to change how novel enzyme catalysts are being created.
Hephaistos is a machine-learning (ML) model that learns from atomistic 3D structure data of existing enzymes. Our model will be able to generate novel catalytic cores for any desired reaction – even on substrates not found in nature.
By constraining the problem size and harnessing the power of equivariant graph neural networks, we significantly increase our hit-rate in discovering suitable enzymes.
The newly generated enzyme core is stabilized and optimized for efficiency, stability and solubility using cutting-edge tools in protein engineering. We do not compete with existing enzyme catalysts, but instead create entirely new ones.
If you want to learn how we can help you catalyze your processes more efficiently – do not hesitate to reach out!
Envision a world where suitable enzyme catalysts are readily available, revolutionizing how we produce chemicals, grow crops, and develop medicines with unmatched precision and sustainability.
Ready to learn more about cutting-edge enzyme catalysis? Learn more from our team.